Author(s):
1. Dejan Pejić, JZU Bolnica Gradiška, Republic of Srpska, Bosnia and Herzegovina
2. Barbara Stanimirović, klinicki centar republike srpske, Republic of Srpska, Bosnia and Herzegovina
3. Božana Galić Pejić, JZU Dom zdravlja Banja Luka , Republic of Srpska, Bosnia and Herzegovina
4. Jelena Mrđa, klinicki centar republike srpske, Republic of Srpska, Bosnia and Herzegovina
5. Vladimir Mrđa, klinicki centar republike srpske, Republic of Srpska, Bosnia and Herzegovina
6. Branka Milošević, JZU Bolnica Gradiška, Republic of Srpska, Bosnia and Herzegovina

Abstract:
Streptococcus agalactiae, also known as Group B Streptococcus (GBS), was first differentiated in the 1930s after it was isolated from milk and cows with bovine mastitis. Colonization of the vaginal tract of women, was not described until 1938. Invasive GBS disease was rarely identified in humans until the 1960s, when increasing reports of adult and neonatal invasive infection. Pregnancy has been associated with a high incidence of invasive GBS disease. Asymptomatic rectovaginal colonization rates among pregnant women vary widely worldwide although the majority of estimates fall between 5%−30%. Group B Streptococcus is the leading etiology of culture-confirmed neonatal bacterial infection in the US and resulting in significant mortality. Invasive neonatal GBS disease may be divided into early onset disease (EOD), occurring <7 days of life, and late onset disease (LOD) occurring between 7–90 days of life. Worldwide, incidences of EOD is 0.09/1000 live births in Japan, 0.58/1000 live births in Panama, 0.76/1000 live births in Hong Kong. Risk factors for EOD disease include maternal vaginal or rectal GBS colonization, GBS bacteriuria during pregnancy, prolonged labor, prolonged rupture of membranes, low birth weight, prematurity, intrapartum fever, and systemic maternal disease. The aim of this study was to examine the prevalence of rectovaginal GBS infection in the population of pregnant women between 35 and 37 weeks of gestation, distribution by parity, age, maternal C reactive protein values, neonatal C reactive protein values, appearance of neonatal skin manifestations and early neonatal infection GBS.

Key words:
Pregnancy, Streptococcus agalactiae, newborn, infection,

Thematic field:
SYMPOSIUM B - Biomaterials and nanomedicine

Date of abstract submission:
05.08.2020.

Conference:
Contemporary Materials 2020 - Savremeni materijali