Author(s):
1. Miloš Papić, Univerzitet u Kragujevcu, Srbija, Fakultet Medicinskih Nauka,, Serbia
2. Milica Popović, Univerzitet u Kragujevcu, Srbija, Fakultet Medicinskih Nauka,, Serbia

Abstract:
Vital pulp therapy involves placing medication on the exposed pulp tissue for the purpose of wound healing with reparatory dentin and preserving the vitality of coronary and radicular pulp of permanent teeth. For years, Ca(OH)2 based materials served as the "gold standard". It’s a strong base witch causes superficial necrosis initiating a pulp tissue response and making of reparatory dentin. The newly formed dentin is generally irregularly shaped with different defects, and the material has poor adhesion properties. The next material that was introduced into practice is mineral trioxide aggregate (MTA). Benefits of MTA, compared to Ca(OH)2, are in its better adhesive properties, less solubility, a thicker layer of reparatory dentin production and causing a weaker inflammatory reaction when in direct contact with the pulp. The application of this material led to improvements in vital pulp therapy. Disadvantages of this material are long setting time, heavy manipulation and staining of teeth. In order to overcome the disadvantages of MTA, newer materials with bioactive properties were designed. Biodentine is a representative of these materials, based on calcium silicate, which is a biocompatible compound. The bioactivity of the material lies in the ability of Biodentine to stimulate the proliferation and differentiation of mesenchymal cells, the rise of the transforming growth factor beta 1 (TGF-ß1) and secretory activity of odontoblasts. Biodentine also shows good dentin adhesion and good marginal sealing. Thanks to its characteristics, this material has improved vital pulp therapy comparing to the materials that are so far known as the "gold standard".

Thematic field:
SYMPOSIUM B - Biomaterials and nanomedicine

Date of abstract submission:
15.07.2016.

Conference:
Contemporary Materials 2016 - Savremeni Materijali

Abstract